Perioperative Bottom‐Up vs. Top‐Down Attention Impairments in Postoperative Delirium
Among older surgical patients, attention impairments associated with POD manifest preoperatively and postoperatively as distinct patterns, namely preoperative impairments in top-down (DAN-regulated) attention processing and postoperative deterioration in top-down (DAN-regulated) and bottom-up (VAN-regulated) processing. Future research should combine the Posner paradigm with EEG/MEG/MRI to pinpoint the source of these POD impairments.
Authors
- Melody Reese (ORCID: https://orcid.org/0000-0002-8288-7914)
- Joseph P. Mathew (ORCID: https://orcid.org/0000-0002-3815-4131)
- Mary Cooter (ORCID: https://orcid.org/0000-0002-0282-552X)
- Kenneth Roberts (ORCID: https://orcid.org/0000-0002-8033-0864)
- Heather Elizabeth Whitson (ORCID: https://orcid.org/0000-0002-8417-4846)
- Michael J. Devinney (ORCID: https://orcid.org/0000-0003-3906-6421)
- Tyler H. Reekes (ORCID: https://orcid.org/0000-0003-4131-1094)
- M. Berger
- Marty G. Woldorff
- Harvey Jay Cohen
- Jeffrey N. Browndyke
Institutions
- University of North Carolina at Charlotte (US)
- Duke University (US)
- Duke Medical Center (US)
- Durham VA Medical Center (US)
- Duke University Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108129
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00