Predicting PET amyloid positivity in the intermediate plasma <i>p</i> ‐tau217 group
In participants with intermediate p -tau217, accuracy of predicting PET A+ status increased modestly (4%) when including existing neuropsychological data. Future work uncovering sensitive cognitive metrics may help enrich screening for PET A+ preclinical trial participants.
Authors
- Henrik Zetterberg
- Tobey J. Betthauser (ORCID: https://orcid.org/0000-0001-8856-1352)
- Kristin E Basche (ORCID: https://orcid.org/0000-0001-5767-8507)
- B. P. Hermann
- Rachael E. Wilson (ORCID: https://orcid.org/0000-0003-4197-7777)
- Ramiro Eduardo Rea Reyes (ORCID: https://orcid.org/0000-0001-9749-282X)
- Kimberly D. Mueller (ORCID: https://orcid.org/0000-0001-8691-9517)
- Sterling C Johnson
- Madeline R Hale
- Rebecca E. Langhough
Institutions
- University of Wisconsin–Madison (US)
- Sahlgrenska University Hospital (SE)
- UK Dementia Research Institute (GB)
- William S. Middleton Memorial Veterans Hospital (US)
- University College London (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108884
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00