Associations of <sup>18</sup> F‐flortaucipir tau PET with quantitative tau histopathology in the medial temporal lobe

Results suggest <sup>18</sup>F-flortaucipir is sensitive to tau burden in early Braak-stage regions and primarily reflects neurofibrillary tangles rather than thread-like tau inclusions.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70862_109873
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Associations of 18 F‐flortaucipir tau PET with quantitative tau histopathology in the medial temporal lobe

Ricardo Gómez Insausti, Amanda E Denning, Ilya M. Nasrallah, Ranjit Ittyerah et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Associations of 18 F‐flortaucipir tau PET with quantitative tau histopathology in the medial temporal lobe

Ricardo Gómez Insausti, Amanda E Denning, Ilya M. Nasrallah, Ranjit Ittyerah, Daniel T. Ohm, Jeffrey S. Phillips, Corey T. McMillan, David A. Wolk, E. B. Lee, John Robinson, Sandhitsu R. Das, Lisa M Levorse, Paul A. Yushkevich, Laura E.M. Wisse, Christopher D. Brown, David J. Irwin, Sanaz Arezoumandan, Sílvia Porta
article en

Abstract

Results suggest <sup>18</sup>F-flortaucipir is sensitive to tau burden in early Braak-stage regions and primarily reflects neurofibrillary tangles rather than thread-like tau inclusions.

Alzheimer s & DementiaVol. 21(S8)
Lund University (SE), Cleveland Clinic Florida (US), University of Castilla-La Mancha (ES), University of Pennsylvania (US)
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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