RAVLT Delayed Recall predicts two‐year changes in cerebrospinal fluid total‐tau for cognitively healthy older adults
Our findings showcase that baseline RAVLT DR performance is a leading indicator of CSF t-tau change over two years in cognitively health older adults. Notably, baseline CSF t-tau level did not predict cognitive change over time. Given the RAVLT's low-cost and ease of administration, it has considerable promise for early prediction of subsequent AD-related fluid biomarker changes later in the disease course.
Authors
- John L. Woodard (ORCID: https://orcid.org/0000-0001-9196-3336)
- Maria Khrestian (ORCID: https://orcid.org/0000-0002-1621-4711)
- Lauren Sather
- Stephen M. Rao
- Audrey Zhu
- Sally Durgerian
- J. Carson Smith
- Kristy A. Nielson
Institutions
- Cleveland Clinic (US)
- Wayne State University (US)
- Medical College of Wisconsin (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108818
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00