RAVLT Delayed Recall predicts two‐year changes in cerebrospinal fluid total‐tau for cognitively healthy older adults

Our findings showcase that baseline RAVLT DR performance is a leading indicator of CSF t-tau change over two years in cognitively health older adults. Notably, baseline CSF t-tau level did not predict cognitive change over time. Given the RAVLT's low-cost and ease of administration, it has considerable promise for early prediction of subsequent AD-related fluid biomarker changes later in the disease course.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108818
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

RAVLT Delayed Recall predicts two‐year changes in cerebrospinal fluid total‐tau for cognitively healthy older adults

John L. Woodard, Maria Khrestian, Lauren Sather, Stephen M. Rao et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

RAVLT Delayed Recall predicts two‐year changes in cerebrospinal fluid total‐tau for cognitively healthy older adults

John L. Woodard, Maria Khrestian, Lauren Sather, Stephen M. Rao, Audrey Zhu, Sally Durgerian, J. Carson Smith, Kristy A. Nielson
article en

Abstract

Our findings showcase that baseline RAVLT DR performance is a leading indicator of CSF t-tau change over two years in cognitively health older adults. Notably, baseline CSF t-tau level did not predict cognitive change over time. Given the RAVLT's low-cost and ease of administration, it has considerable promise for early prediction of subsequent AD-related fluid biomarker changes later in the disease course.

Alzheimer s & DementiaVol. 21(S7)
Cleveland Clinic (US), Wayne State University (US), Medical College of Wisconsin (US), University of Maryland, College Park (US)
Quality Education
Openalex Percentile: Top 35%
Dementia and Cognitive Impairment Research
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