A Multi‐Modal Medical Management and Lifestyle Randomized Clinical Trial Increases Cerebral Blood Flow and Lowers Diabetic Risk in Persons with Early Alzheimer's Disease: Results from The [PREVENTION] Trial

In this small sample, we found evidence that a multi-domain intervention focused on medical management, exercise, and a carbohydrate-restricted diet improved diabetic risk and CBF in patients with AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70860_099523
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

A Multi‐Modal Medical Management and Lifestyle Randomized Clinical Trial Increases Cerebral Blood Flow and Lowers Diabetic Risk in Persons with Early Alzheimer's Disease: Results from The [PREVENTION] Trial

John F. Hodes, Emily S. Popa, Gavin T. Kress, Jennifer E. Bramen et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

A Multi‐Modal Medical Management and Lifestyle Randomized Clinical Trial Increases Cerebral Blood Flow and Lowers Diabetic Risk in Persons with Early Alzheimer's Disease: Results from The [PREVENTION] Trial

John F. Hodes, Emily S. Popa, Gavin T. Kress, Jennifer E. Bramen, Jared C. Roach, Molly K. Rapozo, Ryan M. Glatt, Kyron P. Pierce, Susan Y. Bookheimer, David A. Merrill, William G. Sparks, Colby B. Slyapich, Cyrus A. Raji, Claudia L. Wong, Verna R. Porter, Mihae Kim, Ynez M. Tongson, Prabha Siddarth, Aarthi S. Ganapathi, Stella E. Panos, Tess Bookheimer, Lee Hood, Shannel H. K. Elhelou, Karen J. Miller, Andrea M Torres
article en

Abstract

In this small sample, we found evidence that a multi-domain intervention focused on medical management, exercise, and a carbohydrate-restricted diet improved diabetic risk and CBF in patients with AD.

Alzheimer s & DementiaVol. 21(S6)
University of Southern California (US), University of California, Los Angeles (US), Providence College (US), Washington University in St. Louis (US), Institute for Systems Biology (US), Mallinckrodt (United States) (US), Saint John's Health Center (US), Pacific Heart Institute (US), Drexel University (US), Icahn School of Medicine at Mount Sinai (US)
Openalex Percentile: Top 36%
Dementia and Cognitive Impairment Research
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