The Space Between: Exploring Perivascular Pathways of Alzheimer’s Disease Risk Detection
Our findings suggest that PVS may serve as a marker of early neurodegenerative changes in memory performance, hippocampal structure, and AD pathology, and may be a sensitive biomarker of AD risk in preclinical populations. Future work will examine spatial relationships between PVS and other white matter pathologies.
Authors
- Mithra Sathishkumar (ORCID: https://orcid.org/0000-0003-2572-9618)
- Lauren A Houchin
- Liv McMillan (ORCID: https://orcid.org/0000-0001-5077-7799)
- Jenna N. Adams (ORCID: https://orcid.org/0000-0002-6702-3851)
- Michael A. Yassa (ORCID: https://orcid.org/0000-0002-8635-1498)
- Niels Janssen
- Adam B. Lawrence
- Soyun Kim
- Lisa M. Taylor
Institutions
- Universidad de La Laguna (ES)
- University of California, Irvine (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108149
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00