What's New in <scp>JEACP:</scp> Editor‐in‐Chief's Insights

The article ‘Mycosis Fungoides in Paediatric Patients: A Real-Life Retrospective Study’, signed by Mariana de la Vega et al.1 is a retrospective analysis of a large cohort comprising 123 patients aged 0–18 years with mycosis fungoides (MF) from a single institution. Due to the rarity of MF in children, this series of cases is extremely valuable. All patients presented with early clinical stages (IA/IB), and 70% of cases had hypopigmented MF. Phototherapy was the most frequently indicated treatment, achieving complete remission in more than one-third of the cases (Figure 1). Overall survival after a median follow-up of 19 months was 100%, and no disease progression was seen. Relapse was present in 15% of children. Larger body surface involvement and longer duration of the disease were associated with worse outcomes. Overall, the study confirms a favourable prognosis of MF in children, but long-term follow-up studies are still necessary. Superficial pustular folliculitis of the face and neck is the term given by Huang et al.2 to a seemingly new condition presenting with tiny, superficial follicular pustules on the face and neck, distinct from other well-known facial pustular dermatoses. The authors have compiled 27 Taiwanese patients (26 of whom were female) with this condition, and highlight the recurrent nature of the condition and the good response to topical corticosteroids. On histology, infundibular pustules filled with neutrophils and a perivascular lymphohistiocytic infiltrate in the dermis are seen (Figure 2). Bacteriological studies are consistently negative. More studies involving non-Asian populations are needed to substantiate the description of this new disease. The convenience of the term ‘dysplastic naevus’ is thoughtfully revised by Rosendhal et al.3 The authors critically review the literature and provide evidence that the term ‘dysplastic naevus’, adopted by many pathologists since 1980, merely reflects the wrong interpretation of dysplastic naevi as definitive precursors to melanoma (Figure 3). Therefore, the diagnosis of ‘dysplastic naevus’ is not relevant with respect to prognosis and can complicate therapeutic decision-making for a large proportion of naevi. The authors propose the alternative term ‘borderline melanocytic lesion’ when there is diagnostic uncertainty in melanocytic lesions.

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Publication Details

Journal
Journal of the European Academy of Dermatology and Venereology
Published
2025-12-23
DOI
https://doi.org/10.1111/jdv.70183
Primary Topic
Cutaneous lymphoproliferative disorders research
Type
article
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article

What's New in JEACP: Editor‐in‐Chief's Insights

Antonio Torrelo
Journal of the European Academy of Dermatology and Venereology
Cutaneous lymphoproliferative disorders research
article

What's New in JEACP: Editor‐in‐Chief's Insights

Antonio Torrelo
article en

Abstract

The article ‘Mycosis Fungoides in Paediatric Patients: A Real-Life Retrospective Study’, signed by Mariana de la Vega et al.1 is a retrospective analysis of a large cohort comprising 123 patients aged 0–18 years with mycosis fungoides (MF) from a single institution. Due to the rarity of MF in children, this series of cases is extremely valuable. All patients presented with early clinical stages (IA/IB), and 70% of cases had hypopigmented MF. Phototherapy was the most frequently indicated treatment, achieving complete remission in more than one-third of the cases (Figure 1). Overall survival after a median follow-up of 19 months was 100%, and no disease progression was seen. Relapse was present in 15% of children. Larger body surface involvement and longer duration of the disease were associated with worse outcomes. Overall, the study confirms a favourable prognosis of MF in children, but long-term follow-up studies are still necessary. Superficial pustular folliculitis of the face and neck is the term given by Huang et al.2 to a seemingly new condition presenting with tiny, superficial follicular pustules on the face and neck, distinct from other well-known facial pustular dermatoses. The authors have compiled 27 Taiwanese patients (26 of whom were female) with this condition, and highlight the recurrent nature of the condition and the good response to topical corticosteroids. On histology, infundibular pustules filled with neutrophils and a perivascular lymphohistiocytic infiltrate in the dermis are seen (Figure 2). Bacteriological studies are consistently negative. More studies involving non-Asian populations are needed to substantiate the description of this new disease. The convenience of the term ‘dysplastic naevus’ is thoughtfully revised by Rosendhal et al.3 The authors critically review the literature and provide evidence that the term ‘dysplastic naevus’, adopted by many pathologists since 1980, merely reflects the wrong interpretation of dysplastic naevi as definitive precursors to melanoma (Figure 3). Therefore, the diagnosis of ‘dysplastic naevus’ is not relevant with respect to prognosis and can complicate therapeutic decision-making for a large proportion of naevi. The authors propose the alternative term ‘borderline melanocytic lesion’ when there is diagnostic uncertainty in melanocytic lesions.

Journal of the European Academy of Dermatology and VenereologyVol. 40(1)
Hospital Infantil Universitario Niño Jesús (ES)
Openalex Percentile: Top 25%
Cutaneous lymphoproliferative disorders research
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