Cerebellar degeneration and its integrative role in brain networks for social cognition in early‐stage bvFTD

These results demonstrate that in early-stage bvFTD, cerebellar involvement and its interaction with cerebral network regions may play a more important role in social cognition than previously appreciated. Specifically, posterior cerebellar subregions significantly contribute to social cognitive dysfunction in bvFTD. The observed morphological covariance between cerebellar subregions and cortical social network regions underscores the cerebellum's integrative role within larger brain networks.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70862_110834
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cerebellar degeneration and its integrative role in brain networks for social cognition in early‐stage bvFTD

Electra Chatzidimitriou, Katherine Rankin, Maria Luisa Gorno Tempini, Bruce L. Miller et al.
Alzheimer s & Dementia
Amyotrophic Lateral Sclerosis Research
article

Cerebellar degeneration and its integrative role in brain networks for social cognition in early‐stage bvFTD

Electra Chatzidimitriou, Katherine Rankin, Maria Luisa Gorno Tempini, Bruce L. Miller, William W. Seeley, Joel H Kramer, Howard J. Rosen, Yu Chen
article en

Abstract

These results demonstrate that in early-stage bvFTD, cerebellar involvement and its interaction with cerebral network regions may play a more important role in social cognition than previously appreciated. Specifically, posterior cerebellar subregions significantly contribute to social cognitive dysfunction in bvFTD. The observed morphological covariance between cerebellar subregions and cortical social network regions underscores the cerebellum's integrative role within larger brain networks.

Alzheimer s & DementiaVol. 21(S8)
University of California, San Francisco (US), Aristotle University of Thessaloniki (GR), University Memory and Aging Center (US), University of San Francisco (US)
Quality Education
Openalex Percentile: Top 32%
Amyotrophic Lateral Sclerosis Research
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