Cerebellar degeneration and its integrative role in brain networks for social cognition in early‐stage bvFTD
These results demonstrate that in early-stage bvFTD, cerebellar involvement and its interaction with cerebral network regions may play a more important role in social cognition than previously appreciated. Specifically, posterior cerebellar subregions significantly contribute to social cognitive dysfunction in bvFTD. The observed morphological covariance between cerebellar subregions and cortical social network regions underscores the cerebellum's integrative role within larger brain networks.
Authors
- Electra Chatzidimitriou (ORCID: https://orcid.org/0000-0003-2136-5220)
- Katherine Rankin
- Maria Luisa Gorno Tempini
- Bruce L. Miller
- William W. Seeley
- Joel H Kramer
- Howard J. Rosen
- Yu Chen
Institutions
- University of California, San Francisco (US)
- Aristotle University of Thessaloniki (GR)
- University Memory and Aging Center (US)
- University of San Francisco (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_110834
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00