Analysis of cuproptosis-related genes in head and neck squamous cell carcinoma based on bioinformatics and experimental validation
This study identifies CDKN2A as a suppressor gene for HNSCC, which could serve as a potential biomarker for the diagnosis and treatment of this disease. Additionally, it was noted that CDKN2A mediates the occurrence of cuproptosis by activating antioxidant protective signals.
Authors
- Chunli Li (ORCID: https://orcid.org/0000-0003-4601-9092)
- Qunying Xu
- Jingyi Xie
- Ruiting Huang
- Aixia Zhao
- Meiyang Lu
- Weiqing Huang
- Miaonian Huang
Institutions
- Baise University (CN)
Publication Details
- Journal
- Biochemical and Biophysical Research Communications
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1016/j.bbrc.2025.153186
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00