White Matter Hyperintensities on Brain MRI are Related to Brain Atrophy and Accelerated Brain Age
Increased WMH are related to brain atrophy - in both Alzheimer's and non-Alzheimer's affected regions - and are also related to increased brain age and accelerated brain aging.
Authors
- Rodrigo Solis Pompa
- Saurabh Garg (ORCID: https://orcid.org/0000-0001-8719-284X)
- Yosef Gavriel Chodakiewitz
- Somayeh Meysami (ORCID: https://orcid.org/0000-0001-8550-1397)
- David A. Merrill (ORCID: https://orcid.org/0000-0003-2181-3839)
- Daniel J. Durand (ORCID: https://orcid.org/0000-0001-7290-3135)
- Cyrus A. Raji (ORCID: https://orcid.org/0000-0002-9086-0105)
- Thanh D. Nguyen (ORCID: https://orcid.org/0000-0002-1411-7694)
- Saqib Basar
- Nasrin Akbari
- Sam Hashemi
- Soojin Lee
- Amar Patel
- Ahmed Gouda
Institutions
- Palo Alto University (US)
- Washington University in St. Louis (US)
- Mallinckrodt (United States) (US)
- Saint John's Health Center (US)
- Pacific Heart Institute (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_110308
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00