Roles of <i>APOE</i> e4 in Modulating the Relationship of Non‐genetic Risk Factors with Dementia and Alzheimer’s disease: A System Review and Meta‐analysis of 170 Longitudinal Studies

APOE e4 could interact with other risk factors to influence dementia occurrence. Future studies are needed to validate these interactions and elucidate the underlying mechanisms, enabling precise prediction and prevention of dementia and AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108125
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Roles of APOE e4 in Modulating the Relationship of Non‐genetic Risk Factors with Dementia and Alzheimer’s disease: A System Review and Meta‐analysis of 170 Longitudinal Studies

Wei Xu, Chen‐Chen Tan, Liangyu Huang
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Roles of APOE e4 in Modulating the Relationship of Non‐genetic Risk Factors with Dementia and Alzheimer’s disease: A System Review and Meta‐analysis of 170 Longitudinal Studies

Wei Xu, Chen‐Chen Tan, Liangyu Huang
article en

Abstract

APOE e4 could interact with other risk factors to influence dementia occurrence. Future studies are needed to validate these interactions and elucidate the underlying mechanisms, enabling precise prediction and prevention of dementia and AD.

Alzheimer s & DementiaVol. 21(S7)
Qingdao University (CN), Qingdao Municipal Hospital (CN)
Quality Education
Openalex Percentile: Top 36%
Dementia and Cognitive Impairment Research
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