Longitudinal rate of change in CSF biomarkers is associated with subsequent tau PET burden in Braak stages I and II: Findings from the BIOCARD study

These findings suggest that tau PET burden is preceded by early alterations and more marked changes over time in CSF AD biomarkers. This study extends our understanding of the relationship between CSF and PET measures for tracking AD disease progression.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70862_110116
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Longitudinal rate of change in CSF biomarkers is associated with subsequent tau PET burden in Braak stages I and II: Findings from the BIOCARD study

Anja Soldan, Kylie H. Alm, Corinne Pettigrew, Daniel D. Callow et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Longitudinal rate of change in CSF biomarkers is associated with subsequent tau PET burden in Braak stages I and II: Findings from the BIOCARD study

Anja Soldan, Kylie H. Alm, Corinne Pettigrew, Daniel D. Callow, Jiangxia Wang, Nisha Rani, Arnold Bakker, Michael Miller, Marilyn S. S. Albert, Abhay Moghekar
article en

Abstract

These findings suggest that tau PET burden is preceded by early alterations and more marked changes over time in CSF AD biomarkers. This study extends our understanding of the relationship between CSF and PET measures for tracking AD disease progression.

Alzheimer s & DementiaVol. 21(S8)
Johns Hopkins University (US), Johns Hopkins Medicine (US)
Openalex Percentile: Top 36%
Dementia and Cognitive Impairment Research
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