Longitudinal <sup>123</sup> I‐FP‐CIT SPECT Analysis Using DaTQUANT Software in Autopsy Confirmed Dementia with Lewy Bodies Patients

DaTQUANT using cut-off putamen z-score of -1 was associated with underlying LBD pathology including at their iRBD and MCI stages. Nigrostriatal DaT binding tends to decline over time with DaTQUANT z-score <-2 at their last scans.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70862_110109
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Longitudinal 123 I‐FP‐CIT SPECT Analysis Using DaTQUANT Software in Autopsy Confirmed Dementia with Lewy Bodies Patients

Val J. Lowe, Dennis W. Dickson, Jonathan Graff‐Radford, Scott A. Przybelski et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Longitudinal 123 I‐FP‐CIT SPECT Analysis Using DaTQUANT Software in Autopsy Confirmed Dementia with Lewy Bodies Patients

Val J. Lowe, Dennis W. Dickson, Jonathan Graff‐Radford, Scott A. Przybelski, Tanis J. Ferman, Julie A. Fields, Stuart J. McCarter, Toji Miyagawa, Aivi T. Nguyen, Manoj Jain, David Thomas Jones, Leah K. Forsberg, V. K. Ramanan, Erik K. St. Louis, J. E Parisi, Melissa E. Murray, Cynthia Vernon, Brad F Boeve, Hoon‐Ki Min, Kejal Kantarci, Rodolfo Savica, Neill R. Graff‐Radford, Gregory S Day, R. Ross Reichard
article en

Abstract

DaTQUANT using cut-off putamen z-score of -1 was associated with underlying LBD pathology including at their iRBD and MCI stages. Nigrostriatal DaT binding tends to decline over time with DaTQUANT z-score <-2 at their last scans.

Alzheimer s & DementiaVol. 21(S8)
WinnMed (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Reduced inequalities
Openalex Percentile: Top 36%
Dementia and Cognitive Impairment Research
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Longitudinal <sup>123</sup> I‐FP‐CIT SPECT Analysis Using DaTQUANT Software in Autopsy Confirmed Dementia with Lewy Bodies Patients — Val J. Lowe, Dennis W. Dickson, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS