Sex/gender differences in neurodegeneration pathways linking education to cognitive trajectories among older adults in Korean and US research study cohorts
Our findings highlight potential sex/gender differences in neurobiological pathways linking education to cognition, while differences in effects on memory decline point to differences in mechanisms underlying memory trajectories across cohorts. Future research is needed confirm causal effects and characterize sociocultural factors that may shape educational opportunities and brain health across diverse populations.
Authors
- Evgeny J. Chumin (ORCID: https://orcid.org/0000-0001-6696-6105)
- Stefanie Danielle Piña‐Escudero (ORCID: https://orcid.org/0000-0001-7467-8365)
- Adam M. Staffaroni (ORCID: https://orcid.org/0000-0002-3903-9805)
- Ileana De Anda‐Duran (ORCID: https://orcid.org/0000-0003-3629-9465)
- Kacie Deters
- Jeremy A. Tanner (ORCID: https://orcid.org/0000-0001-9828-1776)
- Talia L. Robinson (ORCID: https://orcid.org/0000-0002-5655-8324)
- Diefei Chen (ORCID: https://orcid.org/0000-0002-9195-3311)
- D. H. Lee
- Meichen Yu (ORCID: https://orcid.org/0009-0009-2228-1417)
- Andrew Joel Saykin
- Kwangsik Nho
- C. Elizabeth Shaaban
- A. Zarina Kraal
- Martine Elbejjani
- Paul K Crane
- Dahyun Yi
- Shannon L Risacher
- Min Soo Byun
Institutions
- Tulane University (US)
- Brigham and Women's Hospital (US)
- Johns Hopkins University (US)
- University of California, Los Angeles (US)
- The University of Texas at San Antonio Health Science Center (US)
- University of Pittsburgh (US)
- University of California, San Francisco (US)
- University of Washington (US)
- Massachusetts General Hospital (US)
- University Memory and Aging Center (US)
- Alzheimer’s Disease Neuroimaging Initiative (US)
- Institute on Aging (US)
- National Medical Center (KR)
- Indiana University School of Medicine
- The University of Texas at San Antonio (US)
- Indiana University – Purdue University Indianapolis (US)
- San Francisco State University (US)
- University of San Francisco (US)
- American University of Beirut (LB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_106933
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00