Engineering chitosan fibers with MSC-exosome cargo: a clinically translatable multifunctional dressing for regenerative therapy in infected wound management

This study successfully developed a chitosan fiber-based exosome composite dressing system, which effectively coordinates infection control and tissue regeneration through a triple mechanism of "structural water-locking, mechanical adaptation, and bioactive synergy." This material provides a scalable solution for chronic wound management and shows promising clinical application prospects.

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Publication Details

Journal
Stem Cell Research & Therapy
Published
2025-12-23
DOI
https://doi.org/10.1186/s13287-025-04863-9
Citations
1
Primary Topic
Wound Healing and Treatments
Type
article
Field-Weighted Citation Impact
1.03
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article

Engineering chitosan fibers with MSC-exosome cargo: a clinically translatable multifunctional dressing for regenerative therapy in infected wound management

Rui Qiao, Di Sun, Dan Jin, Guanjing Lang et al.
1 citations
Stem Cell Research & Therapy
Wound Healing and Treatments
1.03
article

Engineering chitosan fibers with MSC-exosome cargo: a clinically translatable multifunctional dressing for regenerative therapy in infected wound management

Rui Qiao, Di Sun, Dan Jin, Guanjing Lang, Chenyong Fu, Qing Zhang, Zhe Li, Jing Gao
article en
1 citations

Abstract

This study successfully developed a chitosan fiber-based exosome composite dressing system, which effectively coordinates infection control and tissue regeneration through a triple mechanism of "structural water-locking, mechanical adaptation, and bioactive synergy." This material provides a scalable solution for chronic wound management and shows promising clinical application prospects.

Stem Cell Research & TherapyVol. 17(1)
Shanghai Jiao Tong University (CN), Jiaxing University (CN), International Peace Maternity & Child Health Hospital (CN), Shanghai Zhangjiang Laboratory (CN), First Hospital of Jiaxing (CN), National Center for Infectious Diseases (US)
Openalex Percentile: Top 16%
Wound Healing and Treatments
1.03
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