Engineering chitosan fibers with MSC-exosome cargo: a clinically translatable multifunctional dressing for regenerative therapy in infected wound management
This study successfully developed a chitosan fiber-based exosome composite dressing system, which effectively coordinates infection control and tissue regeneration through a triple mechanism of "structural water-locking, mechanical adaptation, and bioactive synergy." This material provides a scalable solution for chronic wound management and shows promising clinical application prospects.
Authors
- Rui Qiao
- Di Sun (ORCID: https://orcid.org/0000-0001-7217-2512)
- Dan Jin
- Guanjing Lang
- Chenyong Fu
- Qing Zhang
- Zhe Li
- Jing Gao
Institutions
- Shanghai Jiao Tong University (CN)
- Jiaxing University (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Shanghai Zhangjiang Laboratory (CN)
- First Hospital of Jiaxing (CN)
- National Center for Infectious Diseases (US)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1186/s13287-025-04863-9
- Citations
- 1
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.03