Sleep health influencing gut microbiome showed an association with cognitive performance
Our findings showed that individuals with good sleep scores had higher cognitive performance, while those with lower sleep scores had lower cognitive performance. The results also indicated an association between gut microbiome and sleep metric as well as between gut microbiome and cognitive performance. Finally, our work revealed that the taxa Clostridium and bolteae exhibited association with both sleep metric and cognitive performance. Further studies should be conducted to understand the effects of sleep metric on the relationship between gut microbiome and the risk of developing Alzheimer's Disease and Related Dementias (ADRD).
Authors
- Sudha S. Seshadri (ORCID: https://orcid.org/0000-0001-6135-2622)
- Yannick N. Wadop (ORCID: https://orcid.org/0000-0002-8955-1874)
- Xueqiu Jian (ORCID: https://orcid.org/0000-0002-0313-6494)
- Biniyam Alemayehu Ayele (ORCID: https://orcid.org/0000-0002-7955-6030)
- Bernard Fongang (ORCID: https://orcid.org/0000-0002-8161-1553)
- Jayandra J. Himali
- Ireneaus Nyame
- Alice Nono Djotsa
- The African Initiative on Bioinformatics Online Training in Neurodegenerative Diseases (AI‐BOND)
- Alfred N. Fonteh
Institutions
- Boston University (US)
- Huntington Medical Research Institutes (US)
- University of Cape Coast (GH)
- University of Miami (US)
- The University of Texas at San Antonio Health Science Center (US)
- Baylor College of Medicine (US)
- Institute for Neurodegenerative Disorders (US)
- Dr. John T. Macdonald Foundation (US)
- Global Brain Health Institute (US)
- Addis Ababa University (ET)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_096594
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00