Frontal Cognitive Impairment and White Matter Hyperintensities in Probable Alzheimer’s Disease
While global cognition and psychiatric symptoms were unaffected by WMH severity, a trend toward reduced frontal function was observed in patients with more severe WMHs. These findings suggest WMHs may contribute to subtle executive dysfunction in AD and warrant further investigation.
Authors
- Jean Seo An
- Mee Young Park
Institutions
- University of Illinois Chicago (US)
- Yeungnam University Medical Center (KR)
- Harrison Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108219
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00