Disparities in Biological Aging and Brain Health: Insights from Diverse Midlife Adults
Accelerated biological aging is associated with increased WMH volume and may contribute to disparities in brain health, particularly among individuals with greater cardiovascular burden. These results highlight the need for targeted, multifaceted interventions that account for sociocultural and biological influences to reduce brain health disparities and promote equity in ADRD outcomes.
Authors
- Justina F. Avila
- Calen P. Ryan (ORCID: https://orcid.org/0000-0002-0550-7949)
- Patrick J. Lao (ORCID: https://orcid.org/0000-0003-2243-3547)
- Daniel W. Belsky (ORCID: https://orcid.org/0000-0001-5463-2212)
- Jennifer J. Manly (ORCID: https://orcid.org/0000-0002-9481-7497)
- Indira C. Turney (ORCID: https://orcid.org/0000-0002-5912-1953)
- Jessica Mazen
- Benjamin Huber (ORCID: https://orcid.org/0000-0003-2876-7177)
- Adam Brickman
- Miguel Arce Rentería
Institutions
- Columbia University Irving Medical Center (US)
- Institute on Aging (US)
- National Institute on Aging (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_109971
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00