Results of a double‐blind sham‐controlled trial examining the effects of hyperbaric oxygen therapy on cognition and brain biomarkers

HBOT did not improve cognitive or brain imaging outcomes compared to sham in older adults with T2D and MCI. A transient cognitive benefit was observed in the sham group immediately post-intervention. The higher rate of SAEs in the HBOT group for this population with high comorbidities warrants further investigation.

Authors

Institutions

Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108814
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Results of a double‐blind sham‐controlled trial examining the effects of hyperbaric oxygen therapy on cognition and brain biomarkers

Ganit Almog, Maayan Harel, Amir Hadanny, Livny Abigail et al.
Alzheimer s & Dementia
Diabetic Foot Ulcer Assessment and Management
article

Results of a double‐blind sham‐controlled trial examining the effects of hyperbaric oxygen therapy on cognition and brain biomarkers

Ganit Almog, Maayan Harel, Amir Hadanny, Livny Abigail, Y. Mardor, Liangyuan Hu, Roy Sagi, Orit H. Lesman‐Segev, Lan Luo, Mary Sano, Ori Benari, Barbara B. Bendlin, Michal Schnaider Beeri, Sapir Golan, Ramit Ravona‐Springer, Shai Efrati
article en

Abstract

HBOT did not improve cognitive or brain imaging outcomes compared to sham in older adults with T2D and MCI. A transient cognitive benefit was observed in the sham group immediately post-intervention. The higher rate of SAEs in the HBOT group for this population with high comorbidities warrants further investigation.

Alzheimer s & DementiaVol. 21(S7)
Rutgers, The State University of New Jersey (US), University of Wisconsin–Madison (US), Bar-Ilan University (IL), Tel Aviv University (IL), Sheba Medical Center (IL), Assaf Harofeh Medical Center (IL), Icahn School of Medicine at Mount Sinai (US)
Openalex Percentile: Top 31%
Diabetic Foot Ulcer Assessment and Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.