Predictive Accuracy of a Clinical Model for Identifying Pathogenic Gene Carriers in Dementia Patients with a Family History at PUMCH
This model demonstrated strong predictive performance in identifying dementia patients at risk of carrying pathogenic variants, supporting its clinical utility in guiding genetic testing. Further research is needed for external validation and refinement.
Authors
- J Y Gao
- F. Feng
- Bo Li (ORCID: https://orcid.org/0000-0002-7294-6888)
- Yuyue Qiu (ORCID: https://orcid.org/0000-0002-9712-2404)
- Li Huo (ORCID: https://orcid.org/0000-0003-1216-083X)
- Y Li
- Jialu Bao (ORCID: https://orcid.org/0000-0001-9407-3339)
- Wenjun Wang (ORCID: https://orcid.org/0000-0003-2890-6878)
- Ying Huang (ORCID: https://orcid.org/0000-0002-4627-1661)
- Wei Jin (ORCID: https://orcid.org/0000-0002-2905-2109)
- Yuhan Jiang (ORCID: https://orcid.org/0009-0001-1098-0722)
- longze sha
- Yunfan You
- Tianyi Wang
- Shanshan Chu
- Chenhui Mao
- Liling Dong
- Meiqi Wu
- Bo Hou
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108047
- Primary Topic
- Genomics and Rare Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00