Genetic Drivers of Progression in Alzheimer's Disease
The absence of a significant association between APOE and AD progression suggests that alternative pathological pathways, beyond amyloid beta, may represent viable targets for impeding disease advancement. These pathways appear to involve neuronal resilience and immune system modulation.
Authors
- Dervis A. M. Salih (ORCID: https://orcid.org/0000-0001-7651-8998)
- Ümran Yaman (ORCID: https://orcid.org/0000-0003-4469-8407)
- Shane Fernandez (ORCID: https://orcid.org/0000-0002-4881-245X)
- Maryam Shoai (ORCID: https://orcid.org/0000-0003-2499-8533)
- J. H. Hardy
- Céleste E. Cohen
- Ahmad R Ehyaei
- Biomarker and Lifestyle (AIBL) Flagship Study of Ageing The Australian Imaging
- Simon M. Laws
- Tenielle Porter
Institutions
- Edith Cowan University (AU)
- Wellcome Sanger Institute (GB)
- Institute of Neurological Sciences (IT)
- UK Dementia Research Institute (GB)
- Max Planck Institute for Intelligent Systems (DE)
- National Hospital for Neurology and Neurosurgery (GB)
- University College London (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108400
- Citations
- 1
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16