Dose‐Response Relationship Between Occupational Exhaust Fume Exposure and Cognitive Decline in Older Adults
Occupational exposure to exhaust fumes is associated with accelerated cognitive decline, with a clear dose-response relationship observed in key cognitive domains. Early declines emphasize the importance of timely interventions to mitigate long-term impacts. Public health measures, such as enhanced workplace ventilation and transitioning to cleaner energy sources, may reduce occupational exposures and protect cognitive health. Future research should adopt longitudinal designs and explore the biological mechanisms underlying these associations and examine other environmental factors that may compound risks.
Authors
- Xinyi Zhang (ORCID: https://orcid.org/0000-0002-3231-5424)
- Perry Elizabeth Sheffield (ORCID: https://orcid.org/0000-0001-9156-1193)
- J LIN
- Tianxu Xia
- Rose Saint Fleur‐Calixte
- Lili Liang
Institutions
- SUNY Downstate Health Sciences University (US)
- Columbia University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_102480
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00