Dose‐Response Relationship Between Occupational Exhaust Fume Exposure and Cognitive Decline in Older Adults

Occupational exposure to exhaust fumes is associated with accelerated cognitive decline, with a clear dose-response relationship observed in key cognitive domains. Early declines emphasize the importance of timely interventions to mitigate long-term impacts. Public health measures, such as enhanced workplace ventilation and transitioning to cleaner energy sources, may reduce occupational exposures and protect cognitive health. Future research should adopt longitudinal designs and explore the biological mechanisms underlying these associations and examine other environmental factors that may compound risks.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70860_102480
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
0.00
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article

Dose‐Response Relationship Between Occupational Exhaust Fume Exposure and Cognitive Decline in Older Adults

Xinyi Zhang, Perry Elizabeth Sheffield, J LIN, Tianxu Xia et al.
Alzheimer s & Dementia
Air Quality and Health Impacts
article

Dose‐Response Relationship Between Occupational Exhaust Fume Exposure and Cognitive Decline in Older Adults

Xinyi Zhang, Perry Elizabeth Sheffield, J LIN, Tianxu Xia, Rose Saint Fleur‐Calixte, Lili Liang
article en

Abstract

Occupational exposure to exhaust fumes is associated with accelerated cognitive decline, with a clear dose-response relationship observed in key cognitive domains. Early declines emphasize the importance of timely interventions to mitigate long-term impacts. Public health measures, such as enhanced workplace ventilation and transitioning to cleaner energy sources, may reduce occupational exposures and protect cognitive health. Future research should adopt longitudinal designs and explore the biological mechanisms underlying these associations and examine other environmental factors that may compound risks.

Alzheimer s & DementiaVol. 21(S6)
SUNY Downstate Health Sciences University (US), Columbia University (US), Icahn School of Medicine at Mount Sinai (US)
Zero hunger
Openalex Percentile: Top 34%
Air Quality and Health Impacts
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