A dual 6‐month (stage 1) & 18‐month (stage 2) prospective, randomized, placebo‐controlled, double‐blind, pivotal clinical trial investigating efficacy and safety of buntanetap in early Alzheimer's patients

Tables will be featured on the poster showing the status of the following per July 2025: • An update of the recruiting sites and locations • A US map with all site locations shown as pins, to highlight regional study access • pTau217 selection inclusion/exclusion figures • Current enrollment versus Target enrollment of 760 participants • Actual monthly participant accrual versus projected monthly accrual • Estimated timelines for the 6-month and 18-month end of study data readouts • Screen failure rate with breakdown of screen failure reasons CONCLUSION: In summary, we will show the ease of using plasma biomarkers to determine the presence of AD. We will provide updates on total enrollment and the 6- and 18-month data readout timepoints.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108764
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

A dual 6‐month (stage 1) & 18‐month (stage 2) prospective, randomized, placebo‐controlled, double‐blind, pivotal clinical trial investigating efficacy and safety of buntanetap in early Alzheimer's patients

Melissa Gaines, Cheng Fang, Maria L. Maccecchini, Matthew J Peterson et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

A dual 6‐month (stage 1) & 18‐month (stage 2) prospective, randomized, placebo‐controlled, double‐blind, pivotal clinical trial investigating efficacy and safety of buntanetap in early Alzheimer's patients

Melissa Gaines, Cheng Fang, Maria L. Maccecchini, Matthew J Peterson, Sarah J MacCallum, Alexander Morin
article en

Abstract

Tables will be featured on the poster showing the status of the following per July 2025: • An update of the recruiting sites and locations • A US map with all site locations shown as pins, to highlight regional study access • pTau217 selection inclusion/exclusion figures • Current enrollment versus Target enrollment of 760 participants • Actual monthly participant accrual versus projected monthly accrual • Estimated timelines for the 6-month and 18-month end of study data readouts • Screen failure rate with breakdown of screen failure reasons CONCLUSION: In summary, we will show the ease of using plasma biomarkers to determine the presence of AD. We will provide updates on total enrollment and the 6- and 18-month data readout timepoints.

Alzheimer s & DementiaVol. 21(S7)
BioChem Technology (United States) (US)
Reduced inequalities
Openalex Percentile: Top 34%
Alzheimer's disease research and treatments
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