Understanding Bilingualism's Protective Effect in Alzheimer's Disease: Exploring Mechanisms of Resilience vs. Resistance
Active bilingualism appears to protect against cognitive decline in individuals with biomarker-confirmed AD, primarily through resilience rather than resistance to AD pathology. Preliminary findings suggest a potential effect of resistance to neuroinflammation is limited to people with AD with low and mid-education levels, which requires further investigation in larger datasets.
Authors
- Olivia Belbin (ORCID: https://orcid.org/0000-0002-6109-6371)
- Marco Calabria (ORCID: https://orcid.org/0000-0003-4373-1316)
- Stephanie M. Grasso (ORCID: https://orcid.org/0000-0001-5287-3012)
- Ignacio Illán‐Gala (ORCID: https://orcid.org/0000-0002-5418-2052)
- Isabel Barroeta (ORCID: https://orcid.org/0000-0003-2764-7923)
- María Carmona‐Iragui (ORCID: https://orcid.org/0000-0001-6914-2339)
- Alexandre Bejanin (ORCID: https://orcid.org/0000-0002-9958-0951)
- Juan M. Fortea (ORCID: https://orcid.org/0000-0002-1340-638X)
- María Belén Sánchez‐Saudinós
- Daniel Alcolea
- Alberto Lleó
- Miguel A Santos‐Santos
- Lídia Vaqué‐Alcázar
- Isabel Sala
Institutions
- Universitat Autònoma de Barcelona (ES)
- Universitat Oberta de Catalunya (ES)
- Instituto de Salud Carlos III (ES)
- Hospital de Sant Pau (ES)
- Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
- The University of Texas at Austin (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_106510
- Primary Topic
- Neurobiology of Language and Bilingualism
- Type
- article
- Field-Weighted Citation Impact
- 0.00