Prognostic Significance and Mechanistic Insights of Rutin-Related Ferroptosis Gene Signature in Hepatocellular Carcinoma

Our findings suggest that rutin may modulate ferroptosis in HCC, with rutin associated ferroptosis genes implicated in disease biology; moreover, the proposed risk scoring model shows promising prognostic utility in HCC.

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Publication Details

Journal
Journal of Hepatocellular Carcinoma
Published
2025-12-01
DOI
https://doi.org/10.2147/jhc.s560755
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic Significance and Mechanistic Insights of Rutin-Related Ferroptosis Gene Signature in Hepatocellular Carcinoma

Danfang Shi, Hai Wang, Zhen Zhang, Xufen Xia et al.
Journal of Hepatocellular Carcinoma
Ferroptosis and cancer prognosis
article

Prognostic Significance and Mechanistic Insights of Rutin-Related Ferroptosis Gene Signature in Hepatocellular Carcinoma

Danfang Shi, Hai Wang, Zhen Zhang, Xufen Xia, Hui Li, Yongle Zhang, Weifeng Yao
article en

Abstract

Our findings suggest that rutin may modulate ferroptosis in HCC, with rutin associated ferroptosis genes implicated in disease biology; moreover, the proposed risk scoring model shows promising prognostic utility in HCC.

Journal of Hepatocellular CarcinomaVol. Volume 12
Nantong University (CN), Tongde Hospital of Zhejiang Province (CN)
Good health and well-being
Openalex Percentile: Top 29%
Ferroptosis and cancer prognosis
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