Plasma Ptau as a Biomarker of Structural Brain Health in the Community
The combination of plasma Ptau181, GFAP, and NfL provide information on the etiology and severity of brain disease in the community. In AD, each are associated with worsening neurodegeneration severity, and NfL is also associated with vascular disease. In individuals with low Ptau181, GFAP is associated with vascular disease.
Authors
- Mitzi M. Gonzales (ORCID: https://orcid.org/0000-0002-8467-0938)
- Sudha S. Seshadri (ORCID: https://orcid.org/0000-0001-6135-2622)
- Jaime Ramos‐Cejudo (ORCID: https://orcid.org/0000-0002-0993-9909)
- R. P. Tracy
- Sara Doyle
- Tiffany F. Kautz (ORCID: https://orcid.org/0000-0001-7680-4708)
- Hugo J. Aparicio (ORCID: https://orcid.org/0000-0001-8584-1455)
- Jeremy A. Tanner (ORCID: https://orcid.org/0000-0001-9828-1776)
- Pauline Maillard (ORCID: https://orcid.org/0000-0003-3516-6345)
- Sophia Francesca DP Lu (ORCID: https://orcid.org/0000-0002-2002-9818)
- C. S. DeCarli
- Jayandra J. Himali
- Mohamad Habes
- Emer McGrath
- Alexa S Beiser
- Claudia L Satizabal
- Terrie‐Jeanne Liu
- Suzanne E. Schindler
Institutions
- Boston University (US)
- University of Vermont (US)
- Cedars-Sinai Medical Center (US)
- The University of Texas at San Antonio Health Science Center (US)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Washington University in St. Louis (US)
- COPE Galway (IE)
- New York University (US)
- University of California, Davis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_110179
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00