Evaluating Volumetric and White Matter Hyperintensity Lesion Measures for Low‐field MRI using WMH‐SynthSeg
WMH-SynthSeg provides comparable volumetric measures to 3T for large brain regions and can spatially capture known ARIA. However, in our small sample, these measures were not sensitive enough to fully identify areas of ARIA. Further development is needed to improve small region quantification and WMH lesion detection, particularly at low-fields.
Authors
- Jessica Banks (ORCID: https://orcid.org/0000-0002-6475-7593)
- Stephen Jarman
- Hope Shimony (ORCID: https://orcid.org/0000-0002-6245-2817)
- Madeline Paczynski
- Alexandra Venuto (ORCID: https://orcid.org/0000-0001-5031-2246)
- Sarah Keefe (ORCID: https://orcid.org/0000-0002-5943-0940)
- Nupur Ghoshal (ORCID: https://orcid.org/0000-0002-6680-6731)
- K. Sharifi (ORCID: https://orcid.org/0000-0001-7434-4613)
- Edmond A. Knopp
- Jude‐Patrick Nnamdi Okafor
- Shaney Flores
- Nelly Joseph‐Mathurin
- B. Joy Snider
- Jessica Hu
- Tammie L.S. Benzinger
- Joo Lim
Institutions
- Washington University in St. Louis (US)
- Prevent Alzheimer’s Disease 2020 (US)
- Infineum (United States) (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70862_110004
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00