MARK4 Suppression Alleviates Tau Pathology and Neurodegeneration in a Mouse Model

MARK4 is critically involved in tau-mediated neurodegeneration. Further characterization of the effects of MARK4-specific inhibitors may lead to a disease-modifying strategy for tauopathies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_099217
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

MARK4 Suppression Alleviates Tau Pathology and Neurodegeneration in a Mouse Model

Junqi Huang
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

MARK4 Suppression Alleviates Tau Pathology and Neurodegeneration in a Mouse Model

Junqi Huang
article en

Abstract

MARK4 is critically involved in tau-mediated neurodegeneration. Further characterization of the effects of MARK4-specific inhibitors may lead to a disease-modifying strategy for tauopathies.

Alzheimer s & DementiaVol. 21(S1)
Tokyo Metropolitan University (JP)
Good health and well-being
Openalex Percentile: Top 34%
Alzheimer's disease research and treatments
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