Is glucose-6-phosphate dehydrogenase deficiency associated with COVID-19 infection, severity, and death? A cohort study from the Brazilian Amazon
In this cohort from the Brazilian Amazon, G6PD deficiency was not associated with an increased risk of COVID-19 infection or severe outcomes. These findings emphasize the importance of considering ethnic and genetic diversity in epidemiological analyses and health policy planning, particularly in regions with high G6PDd prevalence.
Authors
- Gabriel dos Santos Mouta (ORCID: https://orcid.org/0000-0002-5796-9491)
- Marco Aurélio Sartim (ORCID: https://orcid.org/0000-0003-4572-3109)
- Joabi Nascimento
- Patrícia Carvalho da Silva Balieiro (ORCID: https://orcid.org/0000-0002-5221-6319)
- Vanderson de Souza Sampaio
- Wuelton Monteiro MONTEIRO
- Fernando Almeida-Val Almeida-Val
- Marcus V. G. Lacerda
- Jose Diego Brito-Sousa
- Gisely Cardoso de Melo
- Adila L. B. Dias
- Alexandre Vilhena Silva-Neto
- Kamilla Freitas da Silva
- Djane Clarys Baia-da-Silva
Institutions
- University of Siena (IT)
- Duke University (US)
- Fundação de Medicina Tropical (BR)
- Duke Institute for Health Innovation (US)
- Instituto de Saúde (BR)
- Universidade Nilton Lins (BR)
- Escola Superior de Ciências da Saúde (BR)
- Universidade do Estado do Amazonas (BR)
- Fundação Oswaldo Cruz (BR)
- The University of Texas Medical Branch at Galveston (US)
- Universidade Federal do Amazonas (BR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1371/journal.pone.0331729
- Primary Topic
- Neonatal Health and Biochemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado do Amazonas