Linking Microbiome Diversity and Immune Profiles in Ethiopian Patients With Cervical Cancer
Variations in TCR profiles are linked to distinct microbial environments in cervical cancer with greater microbial richness in patients with greater maximum productive frequency. These findings underscore the interplay between TCR diversity, microbiome composition, and malignancy, offering insights into the potential implications for microbiome-targeted therapies and prognostic biomarkers in cervical cancer.
Authors
- Tatiana Cisneros Napravnik
- Ededia Firdawoke (ORCID: https://orcid.org/0000-0002-6357-2044)
- Dzifa Y. Duose (ORCID: https://orcid.org/0000-0002-6763-9736)
- Jessica Lan
- Anuja Jhingran (ORCID: https://orcid.org/0000-0002-0697-1815)
- Cara Haymaker (ORCID: https://orcid.org/0000-0002-1317-9287)
- Brhanu Teka (ORCID: https://orcid.org/0000-0002-0124-6008)
- Zewditu Chanyalew
- T. Abebe
- Lauren E. Colbert (ORCID: https://orcid.org/0000-0001-5806-4339)
- Rajyalakshmi Luthra (ORCID: https://orcid.org/0000-0002-7133-0221)
- Eva Johanna Kantelhardt (ORCID: https://orcid.org/0000-0001-7935-719X)
- Tatiana V. Karpinets (ORCID: https://orcid.org/0000-0002-3668-8148)
- Adane Mihret
- Ann H Klopp
- Adamu Addissie
- Kyoko Yoshida-Court
- Andreas M. Kaufmann
- Muluken Gizaw
- Molly B. El Alam
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Luther University (KR)
- Humboldt-Universität zu Berlin (DE)
- St. Paul's Hospital Millennium Medical College (ET)
- Armauer Hansen Research Institute (ET)
- Addis Ababa University (ET)
- Martin Luther University Halle-Wittenberg (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- JCO Global Oncology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1200/go-25-00060
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00