White Matter Hyperintensities Mediate the Effect of Racial Discrimination on Cognition
These findings highlight the role of WMH as a potential mechanism linking racial discrimination to cognitive health. Results suggest that major life events of racial discrimination are particularly relevant to objective, rather than subjective, cognition, highlighting an important intervention target to improve cognitive health equity. More work is needed to identify policies targeting race-based discrimination to reduce WMH burden and improve cognitive outcomes among older Black adults.
Authors
- Lauren Taylor (ORCID: https://orcid.org/0000-0002-1821-6163)
- Robin Pierce
- Ketlyne Sol (ORCID: https://orcid.org/0000-0001-6716-6927)
- Laura B. Zahodne (ORCID: https://orcid.org/0000-0002-5763-4501)
- Emily P. Morris (ORCID: https://orcid.org/0000-0002-9709-6023)
- Monica Nelson (ORCID: https://orcid.org/0000-0003-0395-5868)
- Jordan D Palms (ORCID: https://orcid.org/0000-0002-5659-4552)
- Kiana A. Scambray (ORCID: https://orcid.org/0000-0002-9618-6385)
- Vivian Ku
Institutions
- University of Michigan (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_106851
- Primary Topic
- Racial and Ethnic Identity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00