Polymers as Stabilizing Excipients for Spray-Dried Protein Formulations
HPβCD and hydrolyzed gelatin improved the physical stability of spray-dried BSA compared to sugar excipients, which highlights their potential use as stabilizing additives.
Authors
- Li Qu
- Navin Kafle
- Haichen Nie (ORCID: https://orcid.org/0009-0006-2748-0026)
- Jiaying Liu (ORCID: https://orcid.org/0000-0002-5376-5790)
- Kinnari Santosh Arte
- Harshil Renawala
- Chanakya Patil
- Qi Tony Zhou
- Yijing Huang
Institutions
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- Purdue University West Lafayette (US)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1007/s11095-025-03996-z
- Primary Topic
- Microencapsulation and Drying Processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00