The Association of Cardiorespiratory Fitness with Rates of Cognitive Decline in a Multiethnic Cohort at Risk for Alzheimer’s Disease
Average and high eCRF were associated with slower cognitive decline in non-URGs, but not in URGs. These group differences may reflect underlying health or lifestyle disparities that influence fitness and cognition. Additionally, the eCRF measure used in this study was developed using data from a predominantly white population; therefore, may not accurately capture fitness status among URGs. This potential limitation should be addressed in future research to improve the accuracy and applicability of eCRF estimates in diverse populations.
Authors
- Carey Elizabeth Gleason (ORCID: https://orcid.org/0000-0001-6210-4671)
- Dane B. Cook (ORCID: https://orcid.org/0000-0002-3992-4820)
- B. P. Hermann
- Brianne M. Breidenbach (ORCID: https://orcid.org/0000-0001-6366-9818)
- Ira Driscoll (ORCID: https://orcid.org/0000-0002-1737-3343)
- Sarah Lose
- Ikenna Stanley Odoh
- Sanjay Asthana (ORCID: https://orcid.org/0000-0002-3998-4479)
- Adam J. Paulsen (ORCID: https://orcid.org/0000-0001-9919-0577)
- Ozioma C. Okonkwo
- Sterling C Johnson
Institutions
- Alzheimer's Association (US)
- University of Wisconsin–Madison (US)
- Geriatric Research Education and Clinical Center (US)
- William S. Middleton Memorial Veterans Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_107989
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00