Simultaneous generation of transplantable RGC-like and corneal progenitor cells from hiPSCs using a dual-lineage platform
Our study establishes a cost-effective surface marker-based method for deriving transplantable RGC and corneal lineage cells from hiPSCs, overcoming key obstacles in ocular regenerative medicine.
Authors
- Jinguo Ye
- Qiuling Hu
- Yingfeng Zheng
- Guilan Li
- Qikai Zhang
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1186/s13287-025-04843-z
- Citations
- 1
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.36