Phenotype Scoring and Personalized Analysis of Population‐Scale Single‐Cell Data Dissects the Complexity of Alzheimer's Disease

Overall, our analyses have advanced in uncovering the cellular and molecular mechanisms underlying diverse AD phenotypes, which has the potential to provide valuable insights for identifying novel diagnostic markers and therapeutic targets. Our results are available through open-source web apps, as well as a personalized single-cell functional genomic atlas for AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_097917
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00
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article

Phenotype Scoring and Personalized Analysis of Population‐Scale Single‐Cell Data Dissects the Complexity of Alzheimer's Disease

Daifeng Wang
Alzheimer s & Dementia
Single-cell and spatial transcriptomics
article

Phenotype Scoring and Personalized Analysis of Population‐Scale Single‐Cell Data Dissects the Complexity of Alzheimer's Disease

Daifeng Wang
article en

Abstract

Overall, our analyses have advanced in uncovering the cellular and molecular mechanisms underlying diverse AD phenotypes, which has the potential to provide valuable insights for identifying novel diagnostic markers and therapeutic targets. Our results are available through open-source web apps, as well as a personalized single-cell functional genomic atlas for AD.

Alzheimer s & DementiaVol. 21(S1)
University of Wisconsin–Madison (US)
Openalex Percentile: Top 37%
Single-cell and spatial transcriptomics
DOIOpen Access PDFOpenAlex
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Phenotype Scoring and Personalized Analysis of Population‐Scale Single‐Cell Data Dissects the Complexity of Alzheimer's Disease — Daifeng Wang · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS