Integrating Contextual Determinants and Polygenic Risk to Examine Dementia and Cognition in the Multi‐Ethnic Study of Atherosclerosis
Neighborhood SES was associated with incident dementia and late-life cognition after adjusting for genetic risk factors and other individual-level risks including education and household income, supporting the need for public health interventions targeting structural determinants of health to reduce dementia risk and improve cognitive outcomes.
Authors
- Diane Xue (ORCID: https://orcid.org/0000-0001-7633-2253)
- Alison E. Fohner (ORCID: https://orcid.org/0000-0003-4231-3331)
- Elizabeth E. Appel Blue
- Timothy M. Hughes
- Wendy Post
Institutions
- Johns Hopkins University (US)
- University of Washington (US)
- Johns Hopkins Medicine (US)
- Wake Forest University (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_101086
- Primary Topic
- Health, Environment, Cognitive Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00