Enhancing the bioavailability of sparingly-soluble drugs by expandable, solid-solution fibrous dosage forms
In dogs the expandable, solid-solution fibrous dosage form enhanced the bioavailability of the sparingly-soluble model drug nilotinib three-fold compared with the present crystalline drug particle-filled capsules.
Authors
- Nannaji Saka
- Aron H. Blaesi (ORCID: https://orcid.org/0000-0002-5467-8103)
- Henning Richter
Institutions
- University of Zurich (CH)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- RSC Pharmaceutics
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1039/d5pm00195a
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universität Zürich
- Innosuisse - Schweizerische Agentur für Innovationsförderung