Multicenter Case Registry Study of Lecanemab in Early Alzheimer's Disease in Northwest China

This real-world study suggests that Lecanemab is well-tolerated in clinical use in Northwest China, with manageable adverse effects and no severe adverse events such as ARIA reported to date. The neuropsychological scales keep stable during the 6-month follow-up, but plasma biomarkers showed significant improvement after treatment. A long time follow-up and large sample are needed.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108419
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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Multicenter Case Registry Study of Lecanemab in Early Alzheimer's Disease in Northwest China

Simeng Cui, Shan Wei, Jin Wang, Ling Gao et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Multicenter Case Registry Study of Lecanemab in Early Alzheimer's Disease in Northwest China

Simeng Cui, Shan Wei, Jin Wang, Ling Gao, Qiumin Qu, Peijie Liu
article en

Abstract

This real-world study suggests that Lecanemab is well-tolerated in clinical use in Northwest China, with manageable adverse effects and no severe adverse events such as ARIA reported to date. The neuropsychological scales keep stable during the 6-month follow-up, but plasma biomarkers showed significant improvement after treatment. A long time follow-up and large sample are needed.

Alzheimer s & DementiaVol. 21(S7)
First Affiliated Hospital of Xi'an Jiaotong University (CN)
Good health and well-being
Openalex Percentile: Top 36%
Dementia and Cognitive Impairment Research
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