Associations Between Alzheimer’s Disease and Rett Syndrome: Clinical Trials of NA‐831 for the Treatment Alzheimer’s and NA‐921 for Rett Syndrome

These findings support a potential mechanistic link between Alzheimer's disease and Rett syndrome. Both NA-831 and NA-921 show promise as novel, well-tolerated therapeutic agents. Further studies are warranted to validate these results and deepen our understanding of the shared molecular pathways between this neurodegenerative and neurodevelopmental disorder.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108250
Primary Topic
Genetics and Neurodevelopmental Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Associations Between Alzheimer’s Disease and Rett Syndrome: Clinical Trials of NA‐831 for the Treatment Alzheimer’s and NA‐921 for Rett Syndrome

Fern Vu, Lloyd Tran, Zung Vu Tran
Alzheimer s & Dementia
Genetics and Neurodevelopmental Disorders
article

Associations Between Alzheimer’s Disease and Rett Syndrome: Clinical Trials of NA‐831 for the Treatment Alzheimer’s and NA‐921 for Rett Syndrome

Fern Vu, Lloyd Tran, Zung Vu Tran
article en

Abstract

These findings support a potential mechanistic link between Alzheimer's disease and Rett syndrome. Both NA-831 and NA-921 show promise as novel, well-tolerated therapeutic agents. Further studies are warranted to validate these results and deepen our understanding of the shared molecular pathways between this neurodegenerative and neurodevelopmental disorder.

Alzheimer s & DementiaVol. 21(S7)
Broomfield Hospital (GB), Biomed Research Institute (US)
Good health and well-being
Openalex Percentile: Top 26%
Genetics and Neurodevelopmental Disorders
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