Shared Plasma Biomarker Signatures Between Sepsis and Alzheimer’s Disease
Our results indicate that sepsis and AD share common biomarkers, suggesting that sepsis may exacerbate AD progression and that both conditions may have overlapping pathophysiological mechanisms. Understanding these similarities could be crucial for developing novel therapies targeting neuroinflammation, neurodegeneration, and PICs.
Authors
- Fabrícia Petronilho (ORCID: https://orcid.org/0000-0003-3240-2808)
- TATIANA BARICHELLO
- Cristiane Ritter (ORCID: https://orcid.org/0000-0002-1891-1561)
- Fernando A. Bozza (ORCID: https://orcid.org/0000-0003-4878-0256)
- Rodrigo A. V. Morales (ORCID: https://orcid.org/0000-0002-7973-356X)
- Mervyn Singer
- Josiane Budni
- Diogo Dominguini
- Felipe Dal‐Pizzol
- Mohd Tayyab
- Bruno Kluwe‐Schiavon
- Giselli Scaini
Institutions
- The London College (GB)
- The University of Texas Health Science Center (US)
- Hospital São Paulo (BR)
- University College London (GB)
- Fundação Oswaldo Cruz (BR)
- Universidade do Extremo Sul Catarinense (BR)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70861_108350
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00