A Primary Cell Culture‐Based Approach for Studying the Pathophysiology of Progressive Supranuclear Palsy (PSP)

This study presents work towards developing an innovative cell culture model to investigate the role of different cytopathologies in the pathogenesis of PSP. The use of cell cultures enables the future incorporation of live imaging of tau trafficking between astrocytes and neurons. This model aims to deepen our understanding of PSP pathogenesis and provide a valuable platform for testing potential therapeutic strategies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70861_108801
Primary Topic
Alzheimer's disease research and treatments
Type
article
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article

A Primary Cell Culture‐Based Approach for Studying the Pathophysiology of Progressive Supranuclear Palsy (PSP)

Priyanka Singh
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

A Primary Cell Culture‐Based Approach for Studying the Pathophysiology of Progressive Supranuclear Palsy (PSP)

Priyanka Singh
article en

Abstract

This study presents work towards developing an innovative cell culture model to investigate the role of different cytopathologies in the pathogenesis of PSP. The use of cell cultures enables the future incorporation of live imaging of tau trafficking between astrocytes and neurons. This model aims to deepen our understanding of PSP pathogenesis and provide a valuable platform for testing potential therapeutic strategies.

Alzheimer s & DementiaVol. 21(S7)
University of Toronto (CA)
Openalex Percentile: Top 34%
Alzheimer's disease research and treatments
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A Primary Cell Culture‐Based Approach for Studying the Pathophysiology of Progressive Supranuclear Palsy (PSP) — Priyanka Singh · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS