Microglia‐containing cerebral organoids model APOE4‐driven Alzheimer's disease pathologies
MCOs can be utilized to study molecular pathways linking APOE4 to DS-AD and compounds were discovered to potentially prevent or delay the onset of DS-AD.
Authors
- Breanna Dooling
- Daphne Quang (ORCID: https://orcid.org/0000-0001-9064-6531)
- Noah R. Johnson (ORCID: https://orcid.org/0000-0002-0969-0066)
- Huntington Potter
- Rose Summers
Institutions
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_098410
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00