Vascular Response After Stenting of the Renal Arteries in Pigs Using an Absorbable Sirolimus-Eluting Polymer Scaffold
Absorbable scaffolds showed sufficient mechanical stability after porcine RA stenting. By incorporation of SIR, a significant reduction of the inflammatory and neointimal response to the unloaded polymer scaffolds was seen without systemic toxicity or thrombotic complications. However, the greater strut height of the polymer scaffold is a major limitation and need to be addressed in future work on the stent design.
Authors
- Sabine Kischkel (ORCID: https://orcid.org/0000-0002-5018-3920)
- Anja Püschel (ORCID: https://orcid.org/0000-0002-1296-3272)
- Carsten Michael Bünger
- David P. Martin (ORCID: https://orcid.org/0000-0002-3132-9576)
- N Grabow
- Simon F. Williams (ORCID: https://orcid.org/0000-0002-4798-7127)
- W. Schareck
Institutions
- Vivantes Klinikum (DE)
- Tepha (United States) (US)
- University of Rostock (DE)
Publication Details
- Journal
- Annals of Vascular Surgery
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1016/j.avsg.2025.12.015
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00