Classifying Dementia and Alzheimer's Disease Participants Using Machine Learning Methods Based on Comorbidities and Lifestyle Factors

This study highlights the potential of machine learning methods, such as XGBoost, to accurately classify participants with diagnosed dementia, Alzheimer's disease, or MCI against a healthy population. By leveraging these features and identifying key predictors through feature importance testing, machine learning methods enhance the precision of participant classification. Additionally, analyzing large publicly available datasets supports the development of future risk prediction models for undiagnosed individuals, ultimately facilitating earlier interventions and improved patient outcomes in dementia care and research.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70860_101861
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Classifying Dementia and Alzheimer's Disease Participants Using Machine Learning Methods Based on Comorbidities and Lifestyle Factors

See Ann Soo, Jermyn Z See, Prem Pillay, Nav Vij et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Classifying Dementia and Alzheimer's Disease Participants Using Machine Learning Methods Based on Comorbidities and Lifestyle Factors

See Ann Soo, Jermyn Z See, Prem Pillay, Nav Vij, Kin Jun See
article en

Abstract

This study highlights the potential of machine learning methods, such as XGBoost, to accurately classify participants with diagnosed dementia, Alzheimer's disease, or MCI against a healthy population. By leveraging these features and identifying key predictors through feature importance testing, machine learning methods enhance the precision of participant classification. Additionally, analyzing large publicly available datasets supports the development of future risk prediction models for undiagnosed individuals, ultimately facilitating earlier interventions and improved patient outcomes in dementia care and research.

Alzheimer s & DementiaVol. 21(S6)
Singapore Polytechnic (SG), Merck (Singapore) (SG)
Good health and well-being
Openalex Percentile: Top 36%
Dementia and Cognitive Impairment Research
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