Thyroid Function and Cognitive Health: Rethinking the Relationship between ‘Suboptimal’ TSH/FT4 Levels and Cognitive Decline
These findings refute claims that higher-normal TSH or low-normal FT4 increases cognitive decline risk, highlighting the need for caution in redefining TSH cutoffs or pursuing unproven thyroid supplementation as a cognitive health intervention.
Authors
- Carlos Roncero (ORCID: https://orcid.org/0000-0002-8712-0843)
- Michael Borrie
- Dvir Dori (ORCID: https://orcid.org/0009-0004-5332-3636)
- Howard Chertkow (ORCID: https://orcid.org/0000-0003-3749-8132)
- Durjoy Lahiri
- Bruna Seixas Lima
Institutions
- Western University (CA)
- Baycrest Hospital (CA)
- Parkwood Institute (CA)
- Kingston Health Sciences Centre (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_103988
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00