Curcumin Ameliorates Aluminum Nanoparticle‐Induced Cognitive Impairment by Enhancing BDNF‐Akt Signaling in the Mouse Hippocampus

These findings suggest that curcumin exerts neuroprotective effects against AlNP-induced cognitive impairment, potentially through the enhancement of BDNF-Akt signaling in the hippocampus. These results highlight the potential therapeutic implications of curcumin as a natural intervention for mitigating the neurotoxic effects of AlNPs.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_097131
Primary Topic
Aluminum toxicity and tolerance in plants and animals
Type
article
Field-Weighted Citation Impact
0.00
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article

Curcumin Ameliorates Aluminum Nanoparticle‐Induced Cognitive Impairment by Enhancing BDNF‐Akt Signaling in the Mouse Hippocampus

S. Ghodsbin Jahromi, Maryam Moosavi
Alzheimer s & Dementia
Aluminum toxicity and tolerance in plants and animals
article

Curcumin Ameliorates Aluminum Nanoparticle‐Induced Cognitive Impairment by Enhancing BDNF‐Akt Signaling in the Mouse Hippocampus

S. Ghodsbin Jahromi, Maryam Moosavi
article en

Abstract

These findings suggest that curcumin exerts neuroprotective effects against AlNP-induced cognitive impairment, potentially through the enhancement of BDNF-Akt signaling in the hippocampus. These results highlight the potential therapeutic implications of curcumin as a natural intervention for mitigating the neurotoxic effects of AlNPs.

Alzheimer s & DementiaVol. 21(S1)
Regional Information Center for Science and Technology (IR), University of Sistan and Baluchestan (IR), Islamic Azad University, Zahedan Branch (IR)
Openalex Percentile: Top 25%
Aluminum toxicity and tolerance in plants and animals
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