Association of prenatal pesticide exposure with plasma Aβ 42/40 and cognitive function in midlife: evidence from the Child Health and Development Studies
Prenatal exposure to p,p'-DDE is associated with lower plasma Aβ 42/40 and worse performance on the DSST in midlife. Identification of individuals or populations more highly exposed to DDT/DDE may identify those at increased risk for ADRD later in life and allow for early intervention and prevention from progression to ADRD.
Authors
- Isha Mhatre‐Winters (ORCID: https://orcid.org/0000-0003-3498-8355)
- Piera M. Cirillo (ORCID: https://orcid.org/0000-0003-4571-4544)
- Young‐Mi Go (ORCID: https://orcid.org/0000-0003-3353-0844)
- Dean P. Jones (ORCID: https://orcid.org/0000-0002-2090-0677)
- Barbara A. Cohn (ORCID: https://orcid.org/0000-0002-9912-8447)
- Nickilou Y. Krigbaum (ORCID: https://orcid.org/0000-0001-5034-7991)
- Pam Factor‐Litvak
- Jason R Richardson
Institutions
- Emory University (US)
- University of Georgia (US)
- Public Health Institute (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70860_107213
- Primary Topic
- Pesticide and Herbicide Environmental Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00