Neoadjuvant chemo-reirradiation followed by resection and intraoperative electron beam radiotherapy: outcomes of multimodality treatment for locally recurrent rectal cancer
In previously irradiated LRRC patients, a multimodality approach combining chemo-reirradiation and extensive surgery with IOERT demonstrated acceptable treatment-related toxicities and favourable oncological outcomes for this high-risk population. Further research with longer follow-up is warranted to identify risk factors associated with treatment-related toxicity.
Authors
- Floor Piqeur (ORCID: https://orcid.org/0000-0002-7465-9866)
- Evi Banken (ORCID: https://orcid.org/0009-0002-6684-0101)
- Joost Nederend
- A. E. Verrijssen
- H. M. U. Peulen
- H. J. T. Rutten
- I. E. G. van Hellemond
- J. W. A. Burger
- J. G. Bloemen
- R. H. N. Tijssen
- C. C. A. Huibregtse Bimmel-Nagel
- D. C. Rijkaart
- J. S. Cnossen
- N. C. Morsink
- F. E. C. Vande Kerckhove
Institutions
- Radboud University Nijmegen (NL)
- Catharina Ziekenhuis (NL)
- Maastricht University (NL)
Publication Details
- Journal
- Radiation Oncology
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1186/s13014-025-02782-w
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- ZonMw