Gut Microbiome Alterations Across Cognitive Decline in Uganda: Phylogenetic and Compositional Insights

Distinct microbial shifts across AD, MCI, and control groups highlight the role of the gut microbiome in neurodegeneration. The transitional profile of MCI underscores its potential as an early marker of dysbiosis, supporting the development of microbiome-targeted strategies for the early detection and intervention of Alzheimer's disease.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_097665
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Gut Microbiome Alterations Across Cognitive Decline in Uganda: Phylogenetic and Compositional Insights

Kamada Lwere
Alzheimer s & Dementia
Gut microbiota and health
article

Gut Microbiome Alterations Across Cognitive Decline in Uganda: Phylogenetic and Compositional Insights

Kamada Lwere
article en

Abstract

Distinct microbial shifts across AD, MCI, and control groups highlight the role of the gut microbiome in neurodegeneration. The transitional profile of MCI underscores its potential as an early marker of dysbiosis, supporting the development of microbiome-targeted strategies for the early detection and intervention of Alzheimer's disease.

Alzheimer s & DementiaVol. 21(S1)
Makerere University (UG)
Openalex Percentile: Top 37%
Gut microbiota and health
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Gut Microbiome Alterations Across Cognitive Decline in Uganda: Phylogenetic and Compositional Insights — Kamada Lwere · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS