Creating a multi‐centre Amyloid PET dataset for DLB patients: Design and Methodology

The creation of a standardized, multi-centre amyloid PET dataset for DLB will enable the study of amyloid PET patterns at the global, regional and voxel level, in comparison with uptake in AD patients and controls. This dataset will serve as a valuable resource for investigating the neuropathological underpinnings of DLB, improving diagnostic accuracy, and potentially guiding patient stratification in anti-amyloid trials. Efforts to integrate [<sup>18</sup>F]Florbetaben and additional data are ongoing.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70862_109944
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Creating a multi‐centre Amyloid PET dataset for DLB patients: Design and Methodology

Val J. Lowe, Ariane Bollack, Cecilia Boccalini, O'Brien John Tiernan et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Creating a multi‐centre Amyloid PET dataset for DLB patients: Design and Methodology

Val J. Lowe, Ariane Bollack, Cecilia Boccalini, O'Brien John Tiernan, Valentina Garibotto, Bernard Hanseeuw, Lisa Quenon, Gill Farrar, Beatrice Orso, Christopher Buckley, Lyduine E. Collij, Giovanni B. Frisoni, Alan J Thomas, Mahnaz Shekari
article en

Abstract

The creation of a standardized, multi-centre amyloid PET dataset for DLB will enable the study of amyloid PET patterns at the global, regional and voxel level, in comparison with uptake in AD patients and controls. This dataset will serve as a valuable resource for investigating the neuropathological underpinnings of DLB, improving diagnostic accuracy, and potentially guiding patient stratification in anti-amyloid trials. Efforts to integrate [<sup>18</sup>F]Florbetaben and additional data are ongoing.

Alzheimer s & DementiaVol. 21(S8)
University of Geneva (CH), Harvard University (US), Lund University (SE), General Electric (Spain) (ES), University of Cambridge (GB), Buckinghamshire Healthcare NHS Trust (GB), Gordon Center for Medical Imaging (US), Massachusetts General Hospital (US), University Hospital of Geneva (CH), Pasqual Maragall Foundation (ES), Amsterdam Neuroscience (NL), Mayo Clinic in Arizona (US), Barcelonaβeta Brain Research Center (ES), Amsterdam University Medical Centers (NL), University College London (GB), Geneva College (US), University of Genoa (IT), Newcastle University (GB), UCLouvain (BE)
Openalex Percentile: Top 36%
Dementia and Cognitive Impairment Research
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